Study: Dengue Infection Becomes More Severe During Second Time

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There are already many diseases identified to be using vectors in order to infect the human populations. These diseases include malaria, dengue, and sleep sickness. Many health care professionals and experts are trying to alarm the public and conduct extensive information drives and campaigns in order to give knowledge to the general public regarding the disease process of these diseases, especially the course on how these diseases are transmitted from one individual to another. Various strategies and methods have been developed by in order to eliminate the vectors which are actually carrying the microorganism causing disease. One of the most commonly encountered diseases transmitted by a vector is the dengue fever which is more common in a locality where there is enough rainfall seasons.

According to a new study which delved on dengue infection, when an individual have been infected for the second time around by dengue, it could be more serious.

Statistics showed that dengue is already becoming a health problem that affects many individual across the globe. In fact, according to the World Health Organization (WHO), the dengue infection is already endemic in about over 100 countries. For this reason, many individuals are becoming at risk of being infected with the said disease. Necessary interventions and strategies must be enforced in order to help protect these individuals from being infected.

The news study which was published in the December issue of Science Translational Medicine was conducted by experts from the University of California, Berkeley. The researchers have discovered the mechanism behind the genetics of the dengue virus and how the immune system of an individual responds to the virus causing dengue.

Basically, dengue virus is classified into four serotypes which include dengue 1, 2, 3 and 4. And each serotypes of the dengue virus can be further classified into smaller subtypes. In the analysis of how the immune system respond to the dengue virus during the first infection, the investigators discovered that the immune system’s response to the second infection can be influenced by the interaction of the immune system and the serotype of dengue virus during the first infection.

Moreover, according to study lead author Molly OhAinle, post-doctoral fellow in infectious diseases at UC Berkeley’s School of Public Health, she said: “with the second infection, the antibodies sort of recognize the new type of viruses, but not well enough to clear them from the system.”





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