Study: Nitroglycerin May Be Effective In Treating Cancers Too

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Improvements and advancements in technology as far as health care is concerned have made significant impact in terms of dealing with certain diseases that afflicts the general population. Certain advancement in the treatment modalities have paved way for a more efficient and yet cost-effective way of treating diseases. However, despite these benefits, there are still other diseases in which many health care professionals are finding a hard time searching for cure, or there are other diseases which need complicated treatment. With this reason, many researchers are conducting studies to find a way which can be used as alternative treatment for a specific disease.

Recently, according to a new study, Nitroglycerin, a medication which is known to help relieve Angina, may also be effective in treating cancer.

Up to this date, there are already various methods and strategies of treating cancer. These methods include chemotherapy, radiation therapy, and surgery. The goals of these treatment modalities are to target the cancer cells and eliminate them from the system of the person with cancer. However, there are certain instances in which cancer cells continue to grow despite aggressive treatment.

The new study which was conducted by the researchers at the Queen’s University and funded by the Canadian Institutes of Health Research (CHIR) in partnership with the Terry Fox Foundation Training Program in Transdisciplinary Cancer Research delved on the potential use of Nitroglycerin as a treatment for cancer. Researchers explained that through the new study they were able to find out a mechanism on how the body’s immune system responds to cancer cells and how come the cancer still progress despite efforts of the immune system to combat the overgrowth of cancer cells.

In the study, the investigators found out an enzyme which is linked to the resistance of cancer cells against the combating efforts of the immune system. This enzyme is known as the ADAM 10 which is actually excessively produced during hypoxic conditions of the cancer cells. In addition, researchers discovered that when these cancer cells are actually treated with Nitroglycerin, the hypoxic conditions of the cancer cells diminished which leads to a decrease in the production of ADAM 10 enzyme, hence, decreasing the resistance of the cancer cells against the immune response.

Moreover, the findings of the new research paved way for the possible use of Nitroglycerin as a treatment for cancer.





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